this post was submitted on 19 Jul 2026
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[–] Senal@programming.dev -3 points 1 day ago* (last edited 1 day ago) (2 children)

That's certainly a definition.

(As a genuine question) How dos that definition account for the placebo effect ?

edit: re-read this and realised it sounded significantly more confrontational than i intended, so i added bracket context.

[–] andros_rex@lemmy.world 11 points 1 day ago (2 children)

“Proof of effectiveness” means a placebo controlled trial. Preferably multiple, with sample sizes substantial enough for sufficient statistical power.

[–] HerbGrower@slrpnk.net 3 points 1 day ago (2 children)

Or we could just start selling placebo tablets and make a fortune. I have some clay in my garden that should be easy enough to shape into pill shapes. We could even paint a few of them red and sell those as extra strong.

Not hurting anyone...

[–] almost1337@lemmy.zip 1 points 16 hours ago

Why waste valuable clay when you can just sell homeopathic remedies?

[–] Jarix@lemmy.world 3 points 1 day ago (1 children)

Um Clay would have an effect. Use powdered sugar and simply compress them into a pill. This is literally one way they do already make placebos in pill form. You can buy a pill press on amazon

[–] HerbGrower@slrpnk.net 1 points 1 day ago (1 children)

Sugar isn't great for diabetics. Wouldn't clay just pass through as it has no nutritional value.

[–] Jarix@lemmy.world 1 points 23 hours ago* (last edited 23 hours ago) (1 children)

Well sure but you could use other household ingredient that aren't contaminated with whatever might be in your soil.

It was intentional that i said it's one way they already make placebos in pill form.

It entirely is only important if you care about hurting people and not just stealing from them.

Which you seem to since you are arguing over diabetes

[–] HerbGrower@slrpnk.net 2 points 19 hours ago (1 children)

People eat clay sometimes. IIRC its a famine thing used to bulk out actual food to make it feel slightly more filling.

Pills are tiny. Wtf do you think the soil is contaminated with?

[–] Jarix@lemmy.world 1 points 16 hours ago

I'm sure they do but not without problems

E coli, anthrax, Lead, mercury, oil, piss, shit, fungus, spores, mold, fucking anything really. You have no idea what's gone into the ground or what it contains. Even if it's "probably" safe why not use a much easier already approved product that has 0 risk associated with it

Unless you are running it through some spectrum analyzer or whatever and have a process to then purify it, it's a bad idea to just ingest something you dug up. And why bother not starting with already human grade ingestible material that you also probably have in your kitchen.

Harmful substances are many orders of magnitude smaller than the tiniest pill.

And no shovels required

[–] Senal@programming.dev 1 points 1 day ago (2 children)

ah, that makes sense.

Does that still apply if the underlying mechanism isn't understood?

I know examples of this exist already , I'm wondering if "proof of effectiveness" really means just the effectiveness in this context.

[–] andros_rex@lemmy.world 7 points 1 day ago (1 children)

Effectiveness is independent of mechanism. As an example, to my knowledge SSRIs don’t really make sense but mostly outperform placebo.

[–] Senal@programming.dev 3 points 1 day ago

Agreed,

Pretty sure anesthesia is similar, (in the not fully understanding the underlying mechanism)

[–] turmacar@lemmy.world 4 points 1 day ago (1 children)

We are only 'pretty sure' of the mechanism of how Tylenol works biochemically as of 2025.

You can test for effectiveness and dangers and everything else you need to prescribe something to get a good idea of whether its actually doing something or not.

'Alternative medicine' is largely, "I felt better after a bit".

[–] HerbGrower@slrpnk.net 2 points 1 day ago

We didn't know how alcohol worked but it was still an effective medicine for battlefield surgeons through history.

[–] Jarix@lemmy.world 2 points 1 day ago (1 children)

I would say how doesn't it?

A placebo is known to NOT work. That medicine has defined, understands and even utilizes the placebo effect is exactly in that definition.

[–] Senal@programming.dev 3 points 1 day ago (1 children)

It's known to potentially have an effect , even if the actual treatment administered was known(by third parties) to be inert and the effect wasnt the one originally planned.

Thats not the same as not working at all.

This is a core part of blind tests, the whole reason you test using a placebo is to isolate the effects that can't be attributed to the actual medicine.

[–] Jarix@lemmy.world 1 points 1 day ago* (last edited 1 day ago) (1 children)

I'm not sure why you are repeating what I said as if I didn't already say that.

Yes, it's known to have an effect. But the placebo itself literally does nothing. It's not a placebo unless it is guaranteed to do nothing or it wouldn't have any value to science with how they use it. Any effect is psychosomatic and NOT an effect of the placebo. Hence the term "placebo effect" this is incredibly important when testing to gather useful data.

I'm guessing you just misunderstood what I was saying since you seem to be repeating me, other than the distinction between placebo and placebo effect

[–] Senal@programming.dev 0 points 23 hours ago (1 children)
  • I asked about the placebo effect, by name.
  • You recited the placebo effect to me like i didn't just mention it directly.
  • I recited it back with extra detail , to make clear that i know what it means.
  • You recited it again, with additional detail, and asked me if i misunderstood your reply containing the definition of the thing i was asking about, by name ?
[–] Jarix@lemmy.world 1 points 22 hours ago* (last edited 22 hours ago) (1 children)

Yeah I know which is why Im confused why you seem to be disagreeinf with me when we are saying the same thing. So I'm repeating myself with different words to try to find where we are having a problem.

I was literally guessing that that might be where the disconnect was. I'm not a great communicator so apologies If I'm just too dumb to figure out whats happening at this point

[–] Senal@programming.dev 0 points 17 hours ago (1 children)

i think the miscommunication was mutual, but started with me, apologies.

[–] Jarix@lemmy.world 1 points 17 hours ago* (last edited 17 hours ago)

Hugs friend all good