this post was submitted on 21 Jan 2026
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[–] JoeBigelow@lemmy.ca 19 points 20 hours ago* (last edited 20 hours ago) (2 children)

Incorrect about acid in the stomach. Most DOX and nbome chems are neutralized by stomach acid and during the mid 2010 acid drought swallowing tabs was considered the simplest way to avoid unwanted DOX trips.

Source: the hundreds of tabs that I swallowed and still had a good time

Edit: Tons of chemicals are active on the hundred microgram scale. Most benzos, nearly all psychedelics, a handful of antipsychotics ect. And if we go active at >10mg, which is impossible to dose without a .000 scale, the list gets even bigger. I appreciate the attempt at an informative post but it's got a few dangerous points of misinformation.

I'm concerned that somebody giving lectures about this topic is as uninformed as you seem to be. Have you taken acid? The subjective experience is as important as the objective. It's like listening to my cop uncle talk about weed but couched in academia.

[–] Rai@lemmy.dbzer0.com 7 points 18 hours ago (1 children)

I took DOC back in the 00s (on purpose) and it was an extremely wild 20-some hours. Second weirdest thing I’ve done (the weirdest is Foxy by a WIDE margin,) but I still had a relatively good time due to having a great and comfortable set and setting. By hour ten, I was VERY ready to be done.

[–] JoeBigelow@lemmy.ca 5 points 18 hours ago (1 children)

I was too poor to care, been on plenty of non acid trips on chems that lasted wayyy too long. Some were really fun, some were abject terror. Never got to try foxy sadly. MXE was the strangest chem I've tried and holey hell, I turned into an interdimentional worm crawling through the multiverse. It was super overwhelming.

[–] Rai@lemmy.dbzer0.com 3 points 14 hours ago (1 children)

I never tried MXE! I wanted to as I have enjoyed ket in the past, but the times I was offered MXE, I just eas not in the right headspace/environment.

Foxy is fucking insane. It had the normal visual and auditory hallucinations, but it’s the only thing I’ve ever tried that gave me full on temporal distortions. My partner-at-the-time and I were listening to familiar music. The music would get lower in pitch and streeeetch out, each individual note playing for longer and longer, until the tone went back to normal and the notes stopped being played for so long. When it was low and slow, our bodies got soooo heavy, we would just lay on the floor. When the notes got fast and higher pitched, our bodies would be light with energy. VERY weird stuff.

[–] JoeBigelow@lemmy.ca 2 points 14 hours ago

MXE and ket are really different. The hole threshold and the visual nature are way stronger ime

[–] daannii@lemmy.world -5 points 15 hours ago* (last edited 14 hours ago) (1 children)

Most drugs/medicines are taken in higher doses because the body filters or neutralizes the compounds so much that only a small portion gets into the blood.

That's still different.

Even if the total quantity of the drug is small in the system once it gets there, it's not the same as how LSD works. The drug, likely because of its similarity to serotonin and size , is readily absorbed into the blood stream and passes the blood brain barrier easily. It is not filtered out to a small percentage of it's original dose like most drugs/medicines.

You surely are aware of this ?

There are very few drugs that can work in small dosages like LSD. As I said, fentanyl is one.

Drugs like DMT /Ayahuasca also can't be ingested unless they are mixed with a maoi inhibitor.

Most psychedelic research chemicals (nbome) are much different than lsd with different pharm and effect properties.

It's possible that LSD is released more quickly on the tongue than nbome drugs. So as soon as it hits the tounge the drug is delivered. I don't think there is research on this. But I'll look into it. I do know that the first trip was caused by a small contact of the drug on someone's hand. That the cleaned off immediately. And it was enough time to absorb a substantial amount of the drug.
I heard women would put on lipstick and smear LSD on the front and kiss police during protest to dose them. If That happened it might support a very fast delivery.
I can't find the source right now to verify the story. I'll keep looking. Maybe I have details wrong. Maybe it was Charles Manson instructing women to do this. Does this story sound familiar to anyone ? I'll have to find the source and verify.

But my point is.

This idea that it's not neutralized in the stomach is false. There is plenty of research on that.

[–] JoeBigelow@lemmy.ca 7 points 14 hours ago* (last edited 14 hours ago) (1 children)

Look up Clonazepam, I'm not going to argue with somebody that is as confidently incorrect as you are. I have a decade and a half of subjective experience and personal research into the chemicals I have put into my body, and spent countless hours talking with people that know even more than I do. Yes, LSD is very active in small amounts. So are plenty of other chemicals and calling it unique because of that is incorrect.

Also, stomach acid does nothing to neutralize LSD in any meaningful way, please stop saying that. You're entire last 2 paragraphs are unsubstantiated myths and things only squares believe. The amount of LSD that Hoffman splashed on his hand likely contained thousands of doses.

I HAVE EATEN HUNDREDS IF NOT THOUSANDS OF HITS OF LSD AND SWALLOW ALMOST EVERY SINGLE ONE OF THEM. SWALLOWING LSD DOES NOT PREVENT IT FROM WORKING. I WILL GIVE YOU TABS TO FUCKING TRY IF YOU WANT

[–] tomiant@piefed.social 5 points 13 hours ago

Yeah this bozo has no clue what they're talking about.