Out of the loop here, what about grapefruit?
(I’ve been eating it like it’s fruit so far…)
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Out of the loop here, what about grapefruit?
(I’ve been eating it like it’s fruit so far…)
Grapefruit is an enzyme inhibitor that blocks clearance of many pharmaceuticals. That's dangerous as it can lead to accidental overdoses despite taking the right dosage.
The person here 'being themselves' needs a 'script to deal with modern society and can't have grapefruit as a result.
I know that your interpretation is most likely what they meant in this meme.
However, I‘m wondering. Is there HRT that you take orally that could be affected by grapefruit too?
In that case there could be a much more positive interpretation of them being told to just be themselves, and they started HRT to achieve exactly that.
I'm not following your question... Grapefruit inhibits the breakdown of meds, it's probably important to appropriately dose HRTs over days/weeks or else there could be some problems with the endocrine systems due to unexpectedly elevated levels (e.g. cardio stuff).
FYI [https://pmc.ncbi.nlm.nih.gov/articles/PMC3589309/] Many of the drugs that interact with grapefruit are highly prescribed and are essential for the treatment of important or common medical conditions. Recently, however, a disturbing trend has been seen. Between 2008 and 2012, the number of medications with the potential to interact with grapefruit and cause serious adverse effects (i.e., torsade de pointes, rhabdomyolysis, myelotoxicity, respiratory depression, gastrointestinal bleeding, nephrotoxicity) has increased from 17 to 43, representing an average rate of increase exceeding 6 drugs per year. This increase is a result of the introduction of new chemical entities and formulations.
Wait, holy shit I think that just explained to me why I'm suddenly "allergic" to grapefruit
The problem with grapefruit is that it enhances the effects variably, which can lead to an unexpected overdose.
I miss grapefruit.
If you drink beer and want to try making your own, you can make a beer (I did a cream ale, if memory serves) using crabapple (the little round red ones usually grown ornamentally) and blueberry, and what results is a hot pink beer that tastes like a less acidic grapefruit.
Its a recipe I came up with afaik, but I used 5 lbs crabapple and 3 lbs blueberry to a 5 gallon cream ale base. Everyone who tried it said it tasted like grapefruit.
I started liking it just before I went on medication 😮💨

I can hear that image.
I only ever saw that clip once and yet I can remember it with more clarity than most
I'll make you feel it.
I don't, I guess I'm lucky.
acid reflux?
Grapefruit interacts with a lot of prescribed medications
was wondering if this was also why grapefruit is a fairly common ingredient in cocktails, and found this delightful factoid:
https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions
The effect was discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol.[9][10]