this post was submitted on 03 Aug 2026
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The feeling sick part is your immune system. :) Most of the feelings we associate with getting sick are the immune response rather than the actual sickness.
The tired feelings are your body telling you to stop moving because it's busy, and also burning energy doing stuff. Joint pain is mostly various tissues getting puffy to make it easier for immune cells to move around. (For sickness. Crunchy ankle is different)
The first two were staggered to maximize the immune response if I recall right, and they also had a bit more kick to them that we tapered down as we learned more about how it all worked.
By the time the next round came about everyone had internalized the vaccine, been exposed and just kicked the living shit out of the virus a few times, and the virus mutated to be a bit weaker.
a little fun fact, TNF-A IS the enzyme, that causes the sick feeling, and triggering/cascade for the other symptoms of feeling sick.